The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 19, 2023
Filed:
Oct. 30, 2020
Massachusetts Institute of Technology, Cambridge, MA (US);
Dana-farber Cancer Institute, Inc., Boston, MA (US);
Alexander K. Shalek, Cambridge, MA (US);
Peter Winter, Cambridge, MA (US);
David Weinstock, Boston, MA (US);
Mark Murakami, Boston, MA (US);
Scott Manalis, Cambridge, MA (US);
Andrew Navia, Cambridge, MA (US);
Jennyfer Galvez-Reyes, Cambridge, MA (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Abstract
Described in exemplary embodiments herein are methods, compositions, and kits for diagnosing, prognosing, monitoring, treating and/or preventing a hemopoietic malignancy and/or relapse thereof in a subject. In some embodiments, the methods can include determining an average cellular mass of cells in a sample from the subject and/or detecting one or more molecular signatures in one or more of the cells. In some embodiments, treatment includes administering one or more BCR-ABL tyrosine kinase inhibitors or a pharmaceutical formulation thereof, one or more pre-BCR signaling pathway inhibitors or a pharmaceutical formulation thereof, one or more p38 MAPK inhibitors or a pharmaceutical formulation thereof; or any combination thereof.