The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 19, 2023

Filed:

Jul. 11, 2019
Applicant:

University of Pittsburgh - of the Commonwealth System of Higher Education, Pittsburgh, PA (US);

Inventor:

Al-Walid A. Mohsen, Gibsonia, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/221 (2006.01); A61P 3/00 (2006.01); A61K 9/00 (2006.01); A61K 31/232 (2006.01);
U.S. Cl.
CPC ...
A61K 31/221 (2013.01); A61K 9/0053 (2013.01); A61K 31/232 (2013.01); A61P 3/00 (2018.01);
Abstract

A method of treating medium chain acyl-CoA dehydrogenase deficiency, very long chain acyl-CoA dehydrogenase deficiency, long chain hydroxyacyl-CoA dehydrogenase deficiency, trifunctional protein deficiency, or CPT II deficiency in a patient is provided comprising administering to the patient a therapeutic amount of a triglyceride or other conjugated fatty acid, that bypasses or leads to an intermediate that bypasses the deficient enzyme. Amino acid-conjugated fatty acids also are provided as well as compositions comprising the amino acid-conjugated fatty acids.


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