The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 19, 2023
Filed:
Sep. 10, 2021
Applicant:
Rush University Medical Center, Chicago, IL (US);
Inventors:
Kalipada Pahan, Skokie, IL (US);
Arunava Ghosh, Chicago, IL (US);
Assignee:
Rush University Medical Center, Chicago, IL (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/07 (2006.01); A61P 25/28 (2006.01); A61K 31/192 (2006.01); A61K 31/203 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/07 (2013.01); A61K 31/192 (2013.01); A61K 31/203 (2013.01); A61P 25/28 (2018.01); A61K 9/0019 (2013.01); A61K 9/0053 (2013.01); A61K 9/0085 (2013.01);
Abstract
The present invention generally relates to compositions and methods for stimulating astroglial uptake and degradation of amyloid-β protein aggregates. One aspect of the invention provides a method of preventing or treating Alzheimer's disease including administrating a clinically effective amount of combination of vitamin A or a derivative thereof and an agonist of proliferator-activated receptor α ('PPARα') to a human or veterinary subject in need of such treatment.