The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 19, 2023

Filed:

Apr. 04, 2022
Applicant:

Akebia Therapeutics, Inc., Cambridge, MA (US);

Inventors:

Alexander Smith, Apex, NC (US);

Gurudatt Ajay Chandorkar, Waltham, MA (US);

Ene Ikpong Ette, Framingham, MA (US);

Bradley John Maroni, Boston, MA (US);

Charlotte Suzanne Hartman, Carmel, IN (US);

Ramin Farzaneh-Far, Brookline, MA (US);

Jula Kern Inrig, Yorba Linda, CA (US);

Assignee:

Akebia Therapeutics, Inc., Cambridge, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4418 (2006.01); A61K 9/20 (2006.01); A61K 9/28 (2006.01); A61K 31/16 (2006.01); C07D 213/81 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4418 (2013.01); A61K 9/2009 (2013.01); A61K 9/2013 (2013.01); A61K 9/2054 (2013.01); A61K 9/2059 (2013.01); A61K 9/2866 (2013.01); A61K 31/16 (2013.01); C07D 213/81 (2013.01);
Abstract

Provided herein are specific doses of, and dosing regimens for, using a HIF prolyl hydroxylase inhibitor in treating or preventing anemia, such as anemia secondary to or associated with chronic kidney disease, anemia secondary to or associated with non-dialysis dependent chronic kidney disease anemia associated with or resulting from chemotherapy, or anemia associated with AIDS.


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