The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 19, 2023

Filed:

Nov. 17, 2022
Applicant:

Endogena Therapeutics, Inc., San Francisco, CA (US);

Inventors:

Matthias Steger, Zurich, CH;

Alex Mueller, Zurich, CH;

Mauro Marigo, Zurich, CH;

Assignee:

ENDOGENA THERAPEUTICS, INC., San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/423 (2006.01); A61P 27/02 (2006.01); A61K 31/422 (2006.01); C07D 413/04 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
A61K 31/423 (2013.01); A61K 31/422 (2013.01); A61P 27/02 (2018.01); C07D 413/04 (2013.01); C07D 413/14 (2013.01);
Abstract

A method of treating and/or preventing disease wherein retinal pigment epithelium, including administering compound of formula (I) or pharmaceutically acceptable salt, racemic mixture, corresponding enantiomer or, if applicable, corresponding diastereomer, wherein: X is either NH or O, R, Rand Rare independently selected from consisting hydrogen group, fluoro, chloro, trifluoromethyl, methyl and difluoromethoxy, A is selected from consisting residue group of formula (II)-(VII) or (VIII) '*' denotes point of attachment to molecule remainder, and R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, Rand Rare independently selected from hydrogen consisting group, linear or branched alkyl having 1-3 carbon atoms, fluoro, chloro, bromo, methoxy, ethoxy, propoxy, trifluoromethyl, 2,2,2-trifluoroethyl and difluoromethoxy and Ris selected from hydrogen consisting group, linear or branched alkyl having 1-3 carbon atoms, trifluoromethyl, and 2,2,2-trifluoroethyl.


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