The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 19, 2023

Filed:

Aug. 15, 2023
Applicant:

Axon Therapies, Inc., New York, NY (US);

Inventors:

Dorin Panescu, San Jose, CA (US);

Andrew Wu, Los Altos Hills, CA (US);

Zoar Jacob Engelman, New York, NY (US);

Mark Gelfand, New York, NY (US);

Mark S. Leung, Duncan, CA;

Assignee:

Axon Therapies, Inc., New York, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61B 18/00 (2006.01); A61B 18/14 (2006.01); A61B 18/02 (2006.01); A61B 90/00 (2016.01); A61B 18/22 (2006.01); A61B 18/12 (2006.01);
U.S. Cl.
CPC ...
A61B 18/1492 (2013.01); A61B 18/0218 (2013.01); A61B 18/1477 (2013.01); A61B 2018/0022 (2013.01); A61B 2018/00267 (2013.01); A61B 2018/00345 (2013.01); A61B 2018/00351 (2013.01); A61B 2018/00434 (2013.01); A61B 2018/00541 (2013.01); A61B 2018/00577 (2013.01); A61B 2018/00666 (2013.01); A61B 2018/00702 (2013.01); A61B 2018/00791 (2013.01); A61B 2018/0212 (2013.01); A61B 2018/126 (2013.01); A61B 2018/1253 (2013.01); A61B 2018/144 (2013.01); A61B 2018/1407 (2013.01); A61B 2018/1425 (2013.01); A61B 2018/1435 (2013.01); A61B 2018/2253 (2017.05); A61B 2090/3966 (2016.02); A61B 2218/002 (2013.01);
Abstract

Systems, devices, and methods for transvascular ablation of target tissue are disclosed herein. The devices and methods may, in some examples, be used for splanchnic nerve ablation to increase splanchnic venous blood capacitance to treat at least one of heart failure and hypertension. For example, the devices disclosed herein may be advanced endovascularly to a target vessel in the region of a thoracic splanchnic nerve (TSN), such as a greater splanchnic nerve (GSN) or a TSN nerve root. Also disclosed are method of treating heart failure, such as HFpEF, by endovascularly ablating a thoracic splanchnic nerve to increase venous capacitance and reduce pulmonary blood pressure.


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