The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 12, 2023

Filed:

Jun. 25, 2019
Applicant:

University of Virginia Patent Foundation, Charlottesville, VA (US);

Inventors:

Boris P. Kovatchev, Charlottesville, VA (US);

Marc D. Breton, Charlottesville, VA (US);

Assignee:

University of Virginia Patent Foundation, Charlottesville, VA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G16H 50/50 (2018.01); G16H 50/20 (2018.01); G16H 10/00 (2018.01); G16B 5/00 (2019.01); G01N 33/487 (2006.01); A61B 5/00 (2006.01); A61B 5/145 (2006.01);
U.S. Cl.
CPC ...
G16H 50/50 (2018.01); A61B 5/14532 (2013.01); A61B 5/7267 (2013.01); G01N 33/48707 (2013.01); G16B 5/00 (2019.02); G16H 10/00 (2018.01); G16H 50/20 (2018.01); A61B 5/4839 (2013.01); A61B 2560/0223 (2013.01); G01N 2800/042 (2013.01);
Abstract

A method, system and computer readable medium for tracking changes in average glycemia in diabetes is based on a conceptually new approach to the retrieval of SMBG data. Using the understanding of HbA1c fluctuation as the measurable effect of the action of an underlying dynamical system, SMBG provides occasional glimpses at the state of this system and, using these measurements, the hidden underlying system trajectory can be reconstructed for individual diabetes patients. Using compartmental modeling a new two-step algorithm is provided that includes: (i) real-time estimate of HbA1c from fasting glucose readings, updated with any new incoming fasting SMBG data point(s), and (ii) initialization and calibration of the estimated HbA1c trace with daily SMBG profiles obtained periodically. The estimation of these profiles includes a factorial model capturing daily BG variability within two latent factors.


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