The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 12, 2023
Filed:
Aug. 19, 2021
Emulate, Inc., Boston, MA (US);
Kyung-Jin Jang, Boston, MA (US);
Janey Ronxhi, Quincy, MA (US);
Josiah Sliz, Boston, MA (US);
Sauveur Jeanty, Canton, MA (US);
Sushma Jadalannagari, Chelmsford, MA (US);
Ananth Nookala, Boston, MA (US);
Hyoungshin Park, Newton, MA (US);
EMULATE, INC., Boston, MA (US);
Abstract
The present invention relates to microfluidic fluidic devices, methods and systems as microfluidic kidney on-chips, e.g. human Proximal Tubule-Kidney-Chip, Glomerulus (Kidney)-Chip, Collecting Duct (Kidney)-Chip. Devices, methods and systems are described for drug testing including drug transport and renal clearance. Further, such devices, methods and systems are used for determining drug-drug interactions and their effect upon renal transporter functions. Importantly, they may be used for pre-clinical and clinical drug development for treating kidney diseases and for personalized medicine.