The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 12, 2023

Filed:

Sep. 22, 2020
Applicant:

Gen-probe Incorporated, San Diego, CA (US);

Inventors:

David Buse, San Diego, CA (US);

David Howard Combs, San Diego, CA (US);

Norbert D. Hagen, Carlsbad, CA (US);

David Opalsky, San Diego, CA (US);

Bruce Richardson, Los Gatos, CA (US);

Anita Prasad, Los Gatos, CA (US);

Keith Moravick, Los Gatos, CA (US);

Tyler Moore, Los Gatos, CA (US);

Byron J. Knight, San Diego, CA (US);

Assignee:

GEN-PROBE INCORPORATED, San Diego, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/686 (2018.01); B01L 7/00 (2006.01); G01N 21/64 (2006.01); B01L 9/06 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/686 (2013.01); B01L 7/52 (2013.01); G01N 21/6452 (2013.01); B01L 9/06 (2013.01); B01L 2200/141 (2013.01); B01L 2200/142 (2013.01); B01L 2300/042 (2013.01); B01L 2300/0654 (2013.01); B01L 2300/0829 (2013.01); B01L 2300/0851 (2013.01); B01L 2300/1822 (2013.01); G01N 2021/6482 (2013.01); G01N 2021/6484 (2013.01);
Abstract

Multiple receptacles containing a reaction mixture are transported to corresponding receptacle wells of a thermally-conductive receptacle holder in thermal communication with a support that is in thermal communication with a heat sink. The heat sink is pre-heated to a temperature above ambient temperature, and the temperature of the receptacle holder is cycled. Optical communication is established between each of the receptacle wells and an excitation signal source and an emission signal detector during cycling, and whether an emission signal is emitted from any of the receptacles is determined as an indication of the presence of a target nucleic acid.


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