The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 12, 2023
Filed:
Sep. 21, 2021
Applicants:
Astrazeneca Ab, Södertälje, SE;
Ionis Pharmaceuticls, Inc., Carlsbad, CA (US);
Inventors:
Daniel Linden, Södertälje, SE;
Richard Lee, Carlsbad, CA (US);
Stefano Romeo, Göthenburg, SE;
Huynh-Hoa Bui, Carlsbad, CA (US);
Assignees:
ASTRAZENECA AB, Södertälje, SE;
IONIS PHARMACEUTICALS, INC., Carisbad, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 15/113 (2010.01); A61P 1/16 (2006.01); A61K 31/713 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 31/713 (2013.01); A61P 1/16 (2018.01); C12N 2310/14 (2013.01); C12N 2310/141 (2013.01); C12N 2310/315 (2013.01); C12N 2310/321 (2013.01); C12N 2310/322 (2013.01); C12N 2310/341 (2013.01); C12N 2310/3519 (2013.01);
Abstract
The present disclosure provides methods of treating or preventing fatty liver disease and/or lowering cholesterol and LDL cholesterol levels in a subject. The present disclosure further provides methods of lowering expression of Pleckstrin and Sec7 Domain Containing 3 (PSD3) in a subject.