The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 12, 2023
Filed:
Jul. 12, 2021
Peking University Shenzhen Graduate School, Shenzhen, CN;
Zhen Yang, Shenzhen, CN;
Qingzhou Zhang, Shenzhen, CN;
Fengxia Li, Shenzhen, CN;
Chongguo Jiang, Shenzhen, CN;
Jianxian Gong, Shenzhen, CN;
Jun Huang, Shenzhen, CN;
Weibin Zhang, Shenzhen, CN;
Peking University Shenzhen Graduate School, Shenzhen, CN;
Abstract
The present disclosure relates to a method of synthesizing cyclosporine derivatives. The method includes: providing a precursor fluid of the cyclosporine derivative, an alkaline fluid and a ClCHOCOCl solution; premixing the precursor fluid and the alkaline fluid to obtain a premixed solution; feeding the premixed solution into a first reaction chamber, reacting to prepare a first reaction liquid; feeding the first reaction liquid into a second reaction chamber, reacting the first reaction liquid with a COfluid to prepare a second reaction liquid; and reacting the second reaction liquid with the ClCHOCOCl solution.