The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 12, 2023
Filed:
Feb. 08, 2018
Dong-a St Co., Ltd., Seoul, KR;
Hyounmie Doh, Yongin-si, KR;
Dongsop Lee, Yongin-si, KR;
Hanyoung Lee, Suwon-si, KR;
Yoojin Kim, Yongin-si, KR;
Kyungmi Han, Suwon-si, KR;
Eunee Jung, Suwon-si, KR;
Donghyeon Kim, Daejeon, KR;
Eongsup Song, Anyang-si, KR;
Kum-Joo Shin, Anyang-si, KR;
Soyon Woo, Seoul, KR;
DONG-A ST CO., LTD., Seoul, KR;
Abstract
The present invention relates to an antibody that specifically binds to death receptor 5 (DR5) and has a function of killing cancer cells. Specifically, provided are an anti-DR5 antibody or antigen-binding fragment thereof, and a use of the antibody or antigen-binding fragment for preventing or treating cancer. The present invention is characterized in that the anti-DR5 antibody or antigen-binding fragment thereof is improved in terms of affinity to DR5, stability, and an effect of killing cancer cells.