The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 12, 2023
Filed:
Mar. 22, 2019
Applicant:
Université Libre DE Bruxelles, Brussels, BE;
Inventor:
Benoit Vanhollebeke, Auderghem, BE;
Assignee:
UNIVERSITÉ LIBRE DE BRUXELLES, Brussels, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/00 (2006.01); C12P 21/02 (2006.01); C12N 15/00 (2006.01); C07K 14/00 (2006.01); A61K 38/00 (2006.01); C07K 14/47 (2006.01); A61P 25/00 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4705 (2013.01); A61P 25/00 (2018.01); G01N 33/5041 (2013.01); A61K 38/00 (2013.01); G01N 2333/726 (2013.01);
Abstract
Novel therapeutic agents, particularly those capable of activating (GPR)124/RECK/Frizzled/lipoprotein receptor-related protein (LRP)-mediated Wnt signaling, while not activating Frizzled/LRP-mediated Wnt signaling in the absence of RECK and/or GPR124. The agents are particularly useful for the prevention or treatment of neurovascular disorders or central nervous system (CNS) disorders including neurovascular dysfunction.