The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 12, 2023

Filed:

Dec. 11, 2020
Applicants:

Biovinc, Llc, Pasadena, CA (US);

University of Southern California, Los Angeles, CA (US);

Inventors:

Frank H. Ebetino, Pasadena, CA (US);

Shuting Sun, Pasadena, CA (US);

Mark W. Lundy, Pasadena, CA (US);

Charles E. McKenna, Pasadena, CA (US);

Eric Richard, Pasadena, CA (US);

Parish Sedghizadeh, Los Angeles, CA (US);

Keivan Sadrerafi, Pasadena, CA (US);

Philip T. Cherian, Pasadena, CA (US);

Assignees:

BIOVINC, LLC, Pasadena, CA (US);

UNIVERSITY OF SOUTHERN CALIFORNIA, Los Angeles, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 9/6558 (2006.01); C07F 9/6561 (2006.01); A61P 31/04 (2006.01); A61P 19/10 (2006.01); A61K 47/55 (2017.01); A61K 47/54 (2017.01);
U.S. Cl.
CPC ...
C07F 9/65583 (2013.01); A61K 47/548 (2017.08); A61K 47/55 (2017.08); A61K 47/552 (2017.08); A61P 19/10 (2018.01); A61P 31/04 (2018.01); C07F 9/6561 (2013.01);
Abstract

Described herein are bisphosphonate quinolone compounds, conjugates and pharmaceutical formulations thereof that can include a bisphosphonate and a quinolone, where the quinolone can be releasably coupled to the bisphosphonate. Also provided herein are methods of making and methods of using the bisphosphonate quinolone compounds, conjugates and pharmaceutical formulations thereof.


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