The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 12, 2023

Filed:

Nov. 25, 2015
Applicants:

Andrew C. Kruegel, New York, NY (US);

Madalee G. Wulf, Beverly, MA (US);

Jonathan A. Javitch, Dobbs Ferry, NY (US);

Dalibor Sames, New York, NY (US);

Inventors:

Andrew C. Kruegel, New York, NY (US);

Madalee G. Wulf, Beverly, MA (US);

Jonathan A. Javitch, Dobbs Ferry, NY (US);

Dalibor Sames, New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/12 (2006.01); C07D 491/18 (2006.01); A61P 25/24 (2006.01); A61P 25/04 (2006.01); C07D 495/18 (2006.01); C07D 471/18 (2006.01); A61K 9/00 (2006.01); A61K 9/70 (2006.01); A61K 31/485 (2006.01); A61K 47/38 (2006.01);
U.S. Cl.
CPC ...
C07D 491/18 (2013.01); A61K 9/0073 (2013.01); A61K 9/7092 (2013.01); A61K 31/485 (2013.01); A61P 25/04 (2018.01); A61P 25/24 (2018.01); C07D 471/18 (2013.01); C07D 495/18 (2013.01); A61K 9/0002 (2013.01); A61K 47/38 (2013.01);
Abstract

The present invention provides a compound having the structure wherein A is a ring structure, with or without substitution; X1 is C or N; X2 is N, O, or S; Y1 is H, -(alkyi), -(alkenyl), -(alkynyl), -(cycloalkyi), (haloalkyi), -(alkyl)-O-(alkyl) or -(alkyl)-(cycloalkyl); Y 2 is H, -(alkyi), -(alkenyl), -(alkynyl), -(cycloalkyi), (haloalkyi), -(alkyl)-O-(alkyl) or -(alkyl)-(cycloalkyl); Y3 is H-(alkyi), -(alkenyl), -(alkynyl), -(cycloalkyi), (haloalkyi), -(alkyl)-O-(alkyl) or -(alkyl)-(cycloalkyl); Y 4 is H-(alkyi), -(alkenyl), -(alkynyl), -(cycloalkyi), (haloalkyi), -(alkyl)-O-(alkyl) or -(alkyl)-(cycloalkyl); Y5 is H, -(alkyi), -(alkenyl), -(alkynyl), -(cycloalkyi), (haloalkyi), -(alkyl)-O-(alkyl) or -(alkyl)-(cycloalkyl); a and P are each present or absent and when present each is a bond.


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