The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 12, 2023
Filed:
Jul. 06, 2022
Escient Pharmaceuticals, Inc., San Diego, CA (US);
Adam Yeager, San Diego, CA (US);
Brandon Selfridge, San Diego, CA (US);
Marcos Sainz, San Diego, CA (US);
Esther Martinborough, San Diego, CA (US);
Marcus Boehm, San Diego, CA (US);
Liming Huang, San Diego, CA (US);
Escient Pharmaceuticals, Inc., San Diego, CA (US);
Abstract
Methods are provided for modulating MRGPR X4 generally, or for treating a MRGPR X4 dependent condition more specifically, by contacting the MRGPR X4 or administering to a subject in need thereof, respectively, an effective amount of a compound having the structure of Formula (I): or a pharmaceutically acceptable isomer, racemate, hydrate, solvate, isotope, or salt thereof, wherein n, x, A, Q, Q, Z, R, R, R, R, Rand Rare as defined herein. Pharmaceutical compositions containing such compounds, as well as to compounds themselves, are also provided.