The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 12, 2023

Filed:

Mar. 13, 2014
Applicant:

W. L. Gore & Associates, Inc., Newark, DE (US);

Inventors:

Paul D Drumheller, Flagstaff, AZ (US);

Robert L. Cleek, Flagstaff, AZ (US);

Todd J. Johnson, Flagstaff, AZ (US);

Theresa A. Holland, Flagstaff, AZ (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61L 27/54 (2006.01); A61L 31/08 (2006.01); A61L 29/16 (2006.01); A61L 29/08 (2006.01); A61L 27/28 (2006.01); A61K 31/337 (2006.01); A61K 31/727 (2006.01); A61K 45/06 (2006.01); A61K 31/436 (2006.01); A61L 31/16 (2006.01); A61L 31/10 (2006.01); A61F 2/07 (2013.01); A61F 2/915 (2013.01); A61L 31/04 (2006.01); A61L 33/00 (2006.01); A61L 33/04 (2006.01); A61L 33/06 (2006.01);
U.S. Cl.
CPC ...
A61L 27/54 (2013.01); A61F 2/07 (2013.01); A61F 2/915 (2013.01); A61K 31/337 (2013.01); A61K 31/436 (2013.01); A61K 31/727 (2013.01); A61K 45/06 (2013.01); A61L 27/28 (2013.01); A61L 29/08 (2013.01); A61L 29/085 (2013.01); A61L 29/16 (2013.01); A61L 31/048 (2013.01); A61L 31/08 (2013.01); A61L 31/10 (2013.01); A61L 31/16 (2013.01); A61L 33/0035 (2013.01); A61L 33/0076 (2013.01); A61L 33/04 (2013.01); A61L 33/064 (2013.01); A61L 2300/216 (2013.01); A61L 2300/416 (2013.01); A61L 2300/42 (2013.01); A61L 2300/602 (2013.01); A61L 2300/606 (2013.01); A61L 2300/61 (2013.01); A61L 2420/02 (2013.01); A61L 2420/06 (2013.01);
Abstract

According to the invention there is provided inter alia a medical device for delivering a therapeutic agent to a tissue, the device having a solid surfactant-free particulate coating layer applied to a surface of the device, the coating layer comprising a therapeutic agent and at least one non-polymeric organic additive which is hydrolytically stable; wherein at least a proportion of the particulate coating layer comprising the therapeutic agent and the at least one organic additive melts as a single phase at a lower temperature than the melting point of the therapeutic agent and the at least one organic additive when in pure form; wherein the therapeutic agent is paclitaxel; and wherein the therapeutic agent, when formulated in the coating layer, is stable to sterilization.


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