The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 12, 2023
Filed:
Nov. 14, 2018
Etablissement Francais Du Sang, La Plaine Saint Denis, FR;
Institut National DE LA Sante ET DE LA Recherche Medicale (Inserm), Paris, FR;
Centre Hospitalier Universitaire DE Besancon, Besançon, FR;
Universite DE Franche Comte, Besancon, FR;
Christophe Ferrand, Dampierre, FR;
Marina Deschamps, Antorpe, FR;
Fabrice Larosa, Velars sur Ouche, FR;
ETABLISSEMENT FRANCAIS DU SANG, La Plaine Saint Denis, FR;
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE, Paris, FR;
CENTRE HOSPITALIER UNIVERSITAIRE DE BESANCON, Besancon, FR;
UNIVERSITE DE FRANCHE COMTE, Besancon, FR;
Abstract
The present invention is relative to an isolated nucleic acid molecule encoding a chimeric antigen receptor (CAR), wherein the CAR comprises an antibody or antibody fragment which includes a anti-IL-1RAP binding domain, polypeptides encoded by this nucleic acid molecule, isolated chimeric antigen receptor (CAR) molecule comprising such an antibody or antibody fragment, a vector comprising a nucleic acid molecule encoding a CAR, as well as a T cell comprising this vector. The present invention is also relative to the use of this T cell (autologous or allogeneic) expressing a CAR molecule to treat a proliferative disease in a mammal.