The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 05, 2023
Filed:
Jul. 15, 2022
Applicant:
The General Hospital Corporation, Boston, MA (US);
Inventors:
Matthew S. Rosen, Somerville, MA (US);
Zdenka Kuncic, Pennant Hills, AU;
David Waddington, Erskineville, AU;
Assignee:
The General Hospital Corporation, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01R 33/561 (2006.01); G01R 33/56 (2006.01); G01R 33/44 (2006.01); A61B 5/055 (2006.01);
U.S. Cl.
CPC ...
G01R 33/5614 (2013.01); A61B 5/055 (2013.01); G01R 33/445 (2013.01); G01R 33/5601 (2013.01); G01R 33/5602 (2013.01); G01R 33/5608 (2013.01);
Abstract
Systems and methods are provided for susceptibility contrast imaging of nanoparticles at low magnetic fields. A susceptibility-based MRI technique, such as imaging with a balanced steady-state free precession (bSSFP) pulse sequence, may be used for imaging a contrast agent such as biocompatible superparamagnetic nanoparticles at ultra-low fields. The contrast agent and imaging technique may be used to improving the visibility of anatomical structures and detecting diseases, such as cancer, with low-field MRI.