The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 05, 2023

Filed:

Sep. 27, 2018
Applicants:

Rosetta Exosome, Seoul, KR;

Postech Academy-industry Foundation, Pohang-si, KR;

Inventors:

Yong Song Gho, Gyeongsangbuk-do, KR;

Chang Jin Lee, Daegu, KR;

Hyun Taek Park, Gyeongsangbuk-do, KR;

Assignee:

ROSETTA EXOSOME, Seoul, KR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 21/64 (2006.01); G01N 33/50 (2006.01); G01N 30/88 (2006.01); C12Q 1/6804 (2018.01); C12Q 1/6837 (2018.01);
U.S. Cl.
CPC ...
G01N 30/88 (2013.01); C12Q 1/6804 (2013.01); C12Q 1/6837 (2013.01); G01N 21/64 (2013.01); G01N 33/5076 (2013.01);
Abstract

The analysis method for extracellular vesicles, according to the present invention, uses the size-specific separation ability of size exclusion chromatography and the properties of a probe that specifically binds with extracellular vesicles, and by using same is capable of the rapid and easy analysis of the quantity of extracellular vesicles included in a sample, analysis of the physicochemical properties of the extracellular vesicles, analysis of the kind and quantity of the components included in the extracellular vesicles, and analysis of the binding properties or affinity of the probe with respect to the components of the extracellular vesicles. In addition, using the analysis method of the present invention not only enables accurate analysis of extracellular vesicles in a sample, without a sample purification or pre-processing step, but also enables accurate and simple analysis of the components of extracellular vesicles, according to the kind of probe, and thus can improve the efficiency of diagnosis using extracellular vesicles. Also, analysis of the properties or affinity of the probe can be applied to, for example, extracellular vesicle-specific antibody screening, protein screening and chemical-substance screening.


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