The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 05, 2023

Filed:

Dec. 20, 2022
Applicant:

Enumerix, Inc., Palo Alto, CA (US);

Inventors:

Eleen Yee Lam Shum, San Carlos, CA (US);

Hei Mun Christina Fan, Palo Alto, CA (US);

Stephen P. A. Fodor, Palo Alto, CA (US);

Janice Hoiyi Lai, Mountain View, CA (US);

Jung Won Keum, Palo Alto, CA (US);

Haeun Grace Lee, Palo Alto, CA (US);

Assignee:

ENUMERIX, INC., Palo Alto, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6876 (2018.01); G01N 21/64 (2006.01); G01N 33/542 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6876 (2013.01); G01N 21/6428 (2013.01); G01N 33/542 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/16 (2013.01); G01N 2021/6439 (2013.01);
Abstract

The disclosure provides compositions, methods, and systems for implementation of highly multiplexed molecular diagnostic assays involving color combinatorics, stimulus-responsive probes, tandem probes, conjugated polymer probes, and other mechanisms for increasing the number of targets that can be simultaneously detected in a digital assay. Multiplexed detection of targets is achieved in a rapid manner, with respect to sample partitioning and target detection using multiple color channels for detection. Implementation of methods described also achieve detection with significantly improved signal-to-noise ratio (SNR) values.


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