The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 05, 2023

Filed:

Apr. 05, 2018
Applicant:

Arizona Board of Regents on Behalf of Arizona State University, Scottsdale, AZ (US);

Inventors:

Nongjian Tao, Fountain Hills, AZ (US);

Shaopeng Wang, Chandler, AZ (US);

Hui Yu, Tempe, AZ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/18 (2006.01); G16H 10/40 (2018.01); G16H 50/20 (2018.01); G16H 30/40 (2018.01); G01N 21/51 (2006.01); G06T 7/00 (2017.01);
U.S. Cl.
CPC ...
C12Q 1/18 (2013.01); G01N 21/51 (2013.01); G06T 7/0012 (2013.01); G16H 10/40 (2018.01); G16H 30/40 (2018.01); G16H 50/20 (2018.01); G01N 2201/1296 (2013.01); G06T 2207/10016 (2013.01); G06T 2207/10056 (2013.01); G06T 2207/20081 (2013.01); G06T 2207/20084 (2013.01); G06T 2207/30024 (2013.01);
Abstract

A method for deep learning video microscopy-based antimicrobial susceptibility testing of a bacterial strain in a sample by acquiring image sequences of individual bacterial cells of the bacterial strain in a subject sample before, during, and after exposure to each antibiotic at different concentrations. The image sequences are compressed into static images while preserving essential phenotypic features. Data representing the static images is input into a pre-trained deep learning (DL) model which generates output data; and antimicrobial susceptibility for the bacterial strain is determined from the output data.


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