The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 05, 2023

Filed:

Feb. 05, 2021
Applicant:

Trustees of Tufts College, Medford, MA (US);

Inventors:

Nikhil U. Nair, Medford, MA (US);

Josef R. Bober, Medford, MA (US);

Assignee:

Trustees of Tufts College, Medford, WI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 19/24 (2006.01); C12N 9/90 (2006.01); C12P 19/02 (2006.01);
U.S. Cl.
CPC ...
C12P 19/24 (2013.01); C12N 9/90 (2013.01); C12P 19/02 (2013.01);
Abstract

Disclosed are components and methods for preparing tagatose from galactose via isomerization reactions using engineered components. The engineered components include microbial cells and methods for preparing microbial cells that have been engineered to catalyze isomerization of galactose to tagatose, in which the microbial cells express cytoplasmically an exogenous L-arabinose isomerase enzyme. The disclosed microbial cells may further be modified for use in methods for preparing tagatose from galactose via isomerization reactions where the microbial cells are treated with reagents that permeabilize the cells. The disclosed methods enable isomerization reactions of galactose to tagatose at relatively high rates, high conversions, and elevated temperatures.


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Nair, Nikhil. (2023). Galactose to tagatose isomerization at moderate temperatures with high conversion and productivity (U.S. Patent No. 11834692). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11834692

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