The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 05, 2023

Filed:

Nov. 06, 2017
Applicant:

Shenzhen Cell Inspire Biotechnology Co., Ltd., Guangdong, CN;

Inventors:

Yubo Yan, Shenzhen, CN;

Jian Fu, Jingshan Country, CN;

Min Zhou, Huaji County, CN;

Yuqing Liu, Shenzhen, CN;

Lixiang Jiang, Shenzhen, CN;

Bo Yang, Wuhan, CN;

Jiayin Yang, Guangzhou, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/074 (2010.01); C12N 5/0793 (2010.01); C12N 15/90 (2006.01); G01N 33/50 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0696 (2013.01); C12N 5/0619 (2013.01); C12N 15/90 (2013.01); G01N 33/5058 (2013.01); G01N 33/6896 (2013.01); C12N 2503/02 (2013.01); C12N 2506/025 (2013.01); C12N 2506/45 (2013.01); C12N 2510/00 (2013.01); C12N 2740/10043 (2013.01); G01N 2333/4709 (2013.01);
Abstract

A method of generating a cellular model of Alzheimer's disease (AD) comprises integrating AD related gene to hiPSC to induce increased beta secretase and/or Abeta 42 peptides, and the cellular model of Alzheimer's disease (AD) is prepared by the method.


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