The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 05, 2023
Filed:
Nov. 24, 2020
Applicant:
Fred Hutchinson Cancer Center, Seattle, WA (US);
Inventors:
Oliver Press, Seattle, WA (US);
Brian Till, Seattle, WA (US);
Assignee:
Fred Hutchinson Cancer Center, Seattle, WA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61P 35/00 (2006.01); A61K 38/00 (2006.01); A61K 39/395 (2006.01); A61K 39/00 (2006.01); C07K 14/725 (2006.01); C07K 16/28 (2006.01); C07K 14/705 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2887 (2013.01); A61K 39/001124 (2018.08); A61K 39/39541 (2013.01); A61K 39/39558 (2013.01); A61P 35/00 (2018.01); C07K 14/7051 (2013.01); C07K 14/70521 (2013.01); A61K 38/00 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); A61K 2039/5156 (2013.01); C07K 2317/24 (2013.01); C07K 2317/622 (2013.01); C07K 2317/73 (2013.01); C07K 2319/03 (2013.01); C07K 2319/33 (2013.01);
Abstract
The present disclosure provides compositions and uses thereof for treating a disease or disorder associated with CD20 expression. Treatments of this disclosure include use of a host cell expressing a fusion protein, such as an anti-CD20 CAR, optionally in combination with a CD20-specific binding molecule, a chemotherapeutic, an inhibitor of an immunosuppression component, or combinations thereof.