The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 05, 2023
Filed:
Sep. 27, 2018
Applicant:
Epicentrx, Inc., La Jolla, CA (US);
Inventors:
Christopher Larson, San Diego, CA (US);
Tony R. Reid, San Diego, CA (US);
Bryan T. Oronsky, Los Altos Hills, CA (US);
Assignee:
EPICENTRX, INC., La Jolla, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/715 (2006.01); A61P 35/00 (2006.01); C07K 14/54 (2006.01); C12N 15/62 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/7155 (2013.01); A61P 35/00 (2018.01); C07K 14/5428 (2013.01); C12N 15/62 (2013.01); A61K 38/00 (2013.01); C07K 2319/03 (2013.01); C07K 2319/30 (2013.01); C07K 2319/50 (2013.01);
Abstract
Provided is a fusion protein, e.g., a cytokine receptor fusion protein, e.g., an IL-10 trap, with a novel linker sequence to permit the fusion protein to functionally optimally, e.g., to permit a cytokine receptor portion of a cytokine receptor fusion protein to bind optimally to its target cytokine. The fusion protein, or an expression vector encoding for the fusion proteins, can be used to treat cell proliferative diseases and disorders, including certain forms of cancer and inflammatory disorders.