The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 05, 2023

Filed:

Mar. 01, 2019
Applicant:

Inflazome Limited, Dublin, IE;

Inventors:

David Miller, Cambridge, GB;

Jimmy Van Wiltenburg, Groningen, NL;

Matthew Cooper, Cambridge, GB;

Assignee:

INFLAZOME LIMITED, Dublin, IE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); C07D 231/18 (2006.01); C07D 405/04 (2006.01); C07D 405/14 (2006.01);
U.S. Cl.
CPC ...
C07D 401/12 (2013.01); C07D 231/18 (2013.01); C07D 405/04 (2013.01); C07D 405/14 (2013.01);
Abstract

The present invention relates to compounds of formula (I): comprising a 5-membered nitrogen-containing heteroaryl ring A, wherein the heteroaryl ring A is substituted with at least one group containing an oxygen atom, and wherein said oxygen atom is attached to the heteroaryl ring A via at least two other atoms. The present invention further relates to salts, solvates and prodrugs of such compounds, to pharmaceutical compositions comprising such compounds, and to the use of such compounds in the treatment and prevention of medical disorders and diseases, most especially by the inhibition of NLRP3.


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