The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 05, 2023
Filed:
Jul. 06, 2020
Applicant:
The Johns Hopkins University, Baltimore, MD (US);
Inventors:
Douglas Robinson, Towson, MD (US);
Alexandra Surcel, Baltimore, MD (US);
Win Pin Ng, Berkeley, CA (US);
Caren L. Freel Meyers, Towson, MD (US);
Assignee:
THE JOHNS HOPKINS UNIVERSITY, Baltimore, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 49/825 (2006.01); A61P 35/00 (2006.01); A61K 31/12 (2006.01); A61K 31/136 (2006.01); A61K 31/15 (2006.01); A61K 31/27 (2006.01); A61K 45/06 (2006.01); C07C 271/58 (2006.01); C07C 275/30 (2006.01); C12Q 1/25 (2006.01); C12Q 1/02 (2006.01); C07C 251/80 (2006.01);
U.S. Cl.
CPC ...
C07C 49/825 (2013.01); A61K 31/12 (2013.01); A61K 31/136 (2013.01); A61K 31/15 (2013.01); A61K 31/27 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07C 251/80 (2013.01); C07C 271/58 (2013.01); C07C 275/30 (2013.01); C12Q 1/025 (2013.01); G01N 2333/44 (2013.01); G01N 2333/4712 (2013.01); G01N 2500/10 (2013.01);
Abstract
Described are methods of treating or preventing a disease in a subject treatable by modulating cell mechanics. The method includes administering to a subject having or at risk for such a disease a pharmaceutical composition. comprising an agent selected from the group comprising a salt, solvate, or stereoisomer of compound (VIII) or its derivatives or a mixture of their constituents, where the compound has the formula: