The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 05, 2023
Filed:
Aug. 31, 2022
Applicant:
Ionis Pharmaceuticals, Inc., Carlsbad, CA (US);
Inventors:
Frank Rigo, Carlsbad, CA (US);
Chrissa A. Dwyer, Collegeville, PA (US);
Assignee:
Ionis Pharmaceuticals, Inc., Carlsbad, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/68 (2017.01); A61K 47/54 (2017.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 47/6849 (2017.08); A61K 47/549 (2017.08); A61K 47/6807 (2017.08); C12N 15/1137 (2013.01); C12N 2310/315 (2013.01); C12N 2310/3231 (2013.01);
Abstract
Provided are oligomeric compounds, methods, and pharmaceutical compositions for DMPK the amount or activity of DMPK RNA in a cell or animal, and in certain instances reducing the amount of DMPK protein in a cell or animal. Such oligomeric compounds, methods, and pharmaceutical compositions are useful to treat type 1 myotonic dystrophy.