The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 05, 2023
Filed:
Sep. 10, 2021
Applicant:
Nammi Therapeutics, Inc., Los Angeles, CA (US);
Inventors:
David Stover, Encino, CA (US);
Dhruba Bharali, Sherman Oaks, CA (US);
Bruce A Hay, Niskayuna, NY (US);
Tahmineh Safaie, Los Angeles, CA (US);
Assignee:
Nammi Therapeutics, Inc., Los Angeles, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/54 (2017.01); A61K 47/69 (2017.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/554 (2017.08); A61K 47/548 (2017.08); A61K 47/549 (2017.08); A61K 47/6911 (2017.08); A61K 47/6929 (2017.08); A61P 35/00 (2018.01);
Abstract
Formulated and/or co-formulated nanocarriers (e.g., LNPs and/or SLNPs) comprising PD-1 Prodrugs and methods of making the nanocarriers are disclosed herein. The PD-1 Prodrug compositions comprise a drug moiety, a lipid moiety, and linkage unit that inhibit PD-1-L1/L2. The PD-1 Prodrugs can be formulated and/or co-formulated into a nanocarrier to provide a method of treating cancer, immunological disorders, and other disease by utilizing a targeted drug delivery vehicle.