The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 05, 2023

Filed:

Feb. 11, 2020
Applicant:

University of Kentucky Research Foundation, Lexington, KY (US);

Inventors:

Luke H. Bradley, Lexington, KY (US);

Don M. Gash, Lexington, KY (US);

Greg A. Gerhardt, Lexington, KY (US);

Raymond T. Bartus, Sr., San Diego, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/08 (2019.01); A61P 25/28 (2006.01); A61P 25/06 (2006.01); A61P 25/24 (2006.01); A61P 25/16 (2006.01);
U.S. Cl.
CPC ...
A61K 38/08 (2013.01); A61P 25/16 (2018.01); A61P 25/24 (2018.01); A61P 25/28 (2018.01);
Abstract

Therapeutic peptides of the following sequence are disclosed: Xaa-Xaa-Xaa-Xaa-Xaa, and optionally further comprising Xaa, wherein Xaa represents an amino acid; Xaais proline; and subscripts represent the positions of each amino acid in the peptide sequence starting from the amino terminus of said peptide extending to the C-terminus. A therapeutic peptide optionally includes a linker that cyclizes the peptide. Also described are methods of treating a neurodegenerative disorder and/or injury in a human subject in need of such treatment by administering to the subject a therapeutically effective amount of a therapeutic peptide as disclosed herein.


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