The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 05, 2023
Filed:
Sep. 17, 2020
Applicants:
Innovative Cellular Therapeutics Holdings, Ltd., Grand Cayman, KY;
Innovative Cellular Therapeutics, Inc., Rockville, MD (US);
Inventors:
Zhiyuan Cao, Shanghai, CN;
Chengfei Pu, Shanghai, CN;
Dongqi Chen, Shanghai, CN;
Wei Ding, Shanghai, CN;
Assignees:
Innovative Cellular Therapeutics Holdings, Ltd., George Town, KY;
Innovative Cellular Therapeutics, Inc., Rockville, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/17 (2015.01); C07K 14/725 (2006.01); C07K 14/705 (2006.01); C07K 16/30 (2006.01); C07K 16/40 (2006.01);
U.S. Cl.
CPC ...
A61K 35/17 (2013.01); C07K 14/7051 (2013.01); C07K 14/70578 (2013.01); C07K 16/3007 (2013.01); C07K 16/3053 (2013.01); C07K 16/40 (2013.01); C07K 2319/03 (2013.01);
Abstract
Embodiments relate to a modified cell comprising a polynucleotide encoding a dominant negative form of Death receptor 5 (DR5). In embodiments, the modified cell further comprises a chimeric antigen receptor (CAR) and/or a modified TCR.