The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 28, 2023
Filed:
Nov. 01, 2017
Public University Corporation Nagoya City University, Nagoya, JP;
Channelosearch Technology, Nagoya, JP;
Yuji Imaizumi, Nagoya, JP;
Hisao Yamamura, Nagoya, JP;
Yoshiaki Suzuki, Nagoya, JP;
Keisuke Kawasaki, Nagoya, JP;
Hiroshi Narita, Saitama, JP;
PUBLIC UNIVERSITY CORPORATION NAGOYA CITY UNIVERSITY, Nagoya, JP;
CHANNELOSEARCH TECHNOLOGY, Nagoya, JP;
Abstract
A screening system provided with a potential-dependent Na ion channel that extends the duration of the action potential associated with depolarization, and a K ion channel that deepens the resting membrane potential in the negative direction, said screening system furthermore including cells provided with ion channels that contribute to deepening the resting membrane potential in the negative direction and/or shortening the duration of the action potential as target ion channels. By such cells, the action of a test compound on the target ion channel can be easily evaluated by providing an inhibitor for the K ion channel to control the probability of cell death.