The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 28, 2023

Filed:

May. 15, 2018
Applicant:

University of Florida Research Foundation, Incorporated, Gainesville, FL (US);

Inventors:

David Tran, Gainesville, FL (US);

Son B. Le, Gainesville, FL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1135 (2013.01); A61K 45/06 (2013.01); C12N 2310/14 (2013.01); C12N 2310/531 (2013.01);
Abstract

Provided herein are immunotherapy compositions for treating a subject with a glioblastoma, comprising a peptide formulation derived from at least one cancer or stemness factor, nanoparticles containing peptides derived from at least one cancer or stemness factor, dendritic cells containing peptides derived from at least one cancer or stemness factors, RNA coding at least one cancer or stemness factor, nanoparticles containing RNA coding at least one cancer or stemness factor, dendritic cells containing RNA coding at least one cancer factor or stemness factor, or an inhibitor of at least one cancer or stemness factor. Also provided are methods of inhibiting a glioblastoma stem-like cell (GSC), methods of treating a subject for glioblastoma, and methods of reprogramming an astrocyte to a glioblastoma stem-like cell (GSC) using such immunotherapy compositions.


Find Patent Forward Citations

Tran, David. (2023). Core master regulators of glioblastoma stem cells (U.S. Patent No. 11827884). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11827884

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