The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 28, 2023
Filed:
Jun. 28, 2019
Applicant:
Crispr Therapeutics Ag, Zug, CH;
Inventors:
Troy Dean Carlo, Cambridge, MA (US);
Roman Lvovitch Bogorad, Cambridge, MA (US);
Assignee:
CRISPR THERAPEUTICS AG, Zug, CH;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/22 (2006.01); C12N 15/90 (2006.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
C12N 15/907 (2013.01); C12N 9/22 (2013.01); C12N 15/11 (2013.01); C12N 2310/18 (2013.01); C12N 2310/20 (2017.05); C12N 2800/80 (2013.01);
Abstract
The present disclosure provides donor polynucleotides, genome editing systems, methods, pharmaceutical compositions, and kits which correct or induce a mutation that causes Glycogen Storage Disease 1a in a genomic DNA molecule in a cell. In some embodiments the present disclosure provides donor polynucleotides comprising two strands capable of correcting a mutation that causes Glycogen Storage Disease 1a.