The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 28, 2023

Filed:

Feb. 25, 2019
Applicants:

Universität Zürich, Zürich, CH;

Eth Zurich, Zürich, CH;

Inventors:

Antoine Florent Herzog, Zürich, CH;

Wendelin Jan Stark, Langenthal, CH;

Martin Zeltner, Feuerthalen, CH;

Beatrice Beck-Schimmer, Zumikon, CH;

Anja Zabel, Zürich, CH;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 17/14 (2006.01); C07K 16/30 (2006.01); A61K 39/395 (2006.01); A61K 47/69 (2017.01); G01N 33/574 (2006.01); G01N 33/553 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 17/14 (2013.01); A61K 39/39558 (2013.01); A61K 47/6929 (2017.08); C07K 16/30 (2013.01); G01N 33/553 (2013.01); G01N 33/57492 (2013.01); A61K 2039/505 (2013.01);
Abstract

The present invention relates to the field of antibodies useful in therapy and diagnosis. It specifically discloses bioconjugates comprising one or more antibodies bound to functionalized, magnetic nanoparticles. These bioconjugates are useful in cancer therapy, particularly for removing circulating tumor cells. The invention further pertains to specific functionalized, magnetic nanoparticles and to the manufacturing of such bioconjugates and such functionalized, magnetic nanoparticles.


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