The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 28, 2023

Filed:

May. 09, 2019
Applicants:

Legochem Biosciences, Inc., Yuseong-gu, KR;

Novimmune, SA, Geneva, CH;

Inventors:

Ho Young Song, Deajeon, KR;

Yun Hee Park, Deajeon, KR;

Sung Min Kim, Daejeon, KR;

Hyoung Rae Kim, Daejeon, KR;

Ji Hye Oh, Daejeon, KR;

Hyun Min Ryu, Daejeon, KR;

Jeiwook Chae, Daejeon, KR;

Yeong Soo Oh, Daejeon, KR;

Yong Zu Kim, Daejeon, KR;

Maureen Deehan, Zug, CH;

Nicolas Fischer, Geneva, CH;

Assignees:

LegoChem Biosciences, Inc., Daejeon, KR;

NovImmune, SA, Geneva, CH;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 47/68 (2017.01); C07H 15/203 (2006.01); A61K 31/5517 (2006.01); A61K 31/7052 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2803 (2013.01); A61K 31/5517 (2013.01); A61K 31/7052 (2013.01); A61K 47/6803 (2017.08); C07H 15/203 (2013.01); A61K 45/06 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/569 (2013.01); C07K 2317/622 (2013.01);
Abstract

The present disclosure relates to antibody-drug conjugates (ADCs) wherein one or more active agents are conjugated to an anti-CD19 antibody through a linker. The linker may comprise a unit that covalently links active agents to the antibody. The disclosure further relates to monoclonal antibodies and antigen binding fragments, variants, multimeric versions, or bispecifics thereof that specifically bind CD19, as well as methods of making and using these anti-CD19 antibodies and antigen-binding fragments thereof in a variety of therapeutic, diagnostic and prophylactic indications.


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