The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 28, 2023
Filed:
Feb. 22, 2023
Applicant:
Glaxosmithkline Biologicals SA, Rixensart, BE;
Inventors:
Kurt Swanson, Newton, MA (US);
Philip R. Dormitzer, Weston, MA (US);
Assignee:
GLAXOSMITHKLINE BIOLOGICALS SA, Rixensart, BE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/10 (2006.01); A61K 39/155 (2006.01); A61K 39/12 (2006.01); C07K 14/005 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/1027 (2013.01); A61K 39/12 (2013.01); A61K 39/155 (2013.01); C07K 14/005 (2013.01); A61K 39/00 (2013.01); A61K 2039/5252 (2013.01); A61K 2039/5256 (2013.01); A61K 2039/5258 (2013.01); A61K 2039/53 (2013.01); A61K 2039/55505 (2013.01); A61K 2039/55555 (2013.01); A61K 2039/55561 (2013.01); A61K 2039/55566 (2013.01); A61K 2039/55572 (2013.01); C07K 2317/76 (2013.01); C07K 2319/00 (2013.01); C07K 2319/21 (2013.01); C07K 2319/50 (2013.01); C07K 2319/73 (2013.01); C12N 2760/18522 (2013.01); C12N 2760/18534 (2013.01); C12N 2770/36143 (2013.01);
Abstract
The present invention relates to immunogenic compositions comprising RSV F protein, methods for preparing compositions that contain RSV F protein ecto-domain polypeptides, and to certain engineered RSV F proteins and nucleic acids that encode the engineered RSV F proteins. Compositions prepared using the methods can contain RSV F protein ecto-domain polypeptides in a predominant or single desired form and conformation. The invention also relates to methods for inducing an immune response to RSV F.