The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 28, 2023

Filed:

Jun. 22, 2020
Applicant:

Inhibrx, Inc., La Jolla, CA (US);

Inventors:

Brendan P. Eckelman, La Jolla, CA (US);

John C. Timmer, La Jolla, CA (US);

Peter L. Nguy, La Jolla, CA (US);

Grant B. Guenther, La Jolla, CA (US);

Quinn Deveraux, La Jolla, CA (US);

Assignee:

InhibRx, Inc., La Jolla, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/81 (2006.01); A61K 38/00 (2006.01); C07K 16/40 (2006.01); C07K 14/715 (2006.01); C07K 16/24 (2006.01); C07K 14/525 (2006.01); C07K 14/76 (2006.01); C07K 14/765 (2006.01);
U.S. Cl.
CPC ...
C07K 14/8125 (2013.01); A61K 38/00 (2013.01); C07K 14/811 (2013.01); C07K 14/8121 (2013.01); C07K 16/40 (2013.01); C07K 14/525 (2013.01); C07K 14/7151 (2013.01); C07K 14/7155 (2013.01); C07K 14/76 (2013.01); C07K 14/765 (2013.01); C07K 16/241 (2013.01); C07K 2317/52 (2013.01); C07K 2317/522 (2013.01); C07K 2317/524 (2013.01); C07K 2317/526 (2013.01); C07K 2317/53 (2013.01); C07K 2317/56 (2013.01); C07K 2319/00 (2013.01); C07K 2319/30 (2013.01); C07K 2319/31 (2013.01); C07K 2319/70 (2013.01);
Abstract

This invention relates to molecules, particularly polypeptides, more particularly fusion proteins that include a serpin polypeptide or an amino acid sequence that is derived from a serpin and second polypeptide comprising of at least one the following: an Fc polypeptide or an amino acid sequence that is derived from an Fc polypeptide; a cytokine targeting polypeptide or a sequence derived from a cytokine targeting polypeptide; a (whey acidic protein) WAP domain containing polypeptide or a sequence derived from a WAP containing polypeptide; and an albumin polypeptide or an amino acid sequence that is derived from a serum albumin polypeptide. This invention also relates to methods of using such molecules in a variety of therapeutic and diagnostic indications, as well as methods of producing such molecules.


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