The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 28, 2023
Filed:
Aug. 29, 2019
University of Miyazaki, Miyazaki, JP;
UNIVERSITY OF MIYAZAKI, Miyazaki, JP;
Abstract
[Problem] To develop a technique that can stabilize the higher-order structure of a nucleic acid and can be used in analysis of nucleic acid structure. [Solution] This guanosine derivative compound is represented by formula 1. In the formula, one of Rand Rrepresents H, and the other represents any of H, OH, OCH, and F, Rrepresents a functional group that is for detection and that hasF, Rrepresents an amine-protecting group, Rrepresents a hydroxy group-protecting group, and Rrepresents an introduction group that is to be introduced into a nucleic acid oligomer. This guanosine derivative compound can be introduced as a part of a nucleic acid sequence, and the introduced nucleic acid oligomer stabilizes the higher-order structure in a nucleic acid, and enables dynamic detection byF NMR.