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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11827582 B1

PDFFull Text
Date of Patent:
Nov. 28, 2023

Filed:

Mar. 31, 2020

Substituted amines as disrupters of abeta42 oligomer formation

Applicant:

Acelot, Inc., Palo Alto, CA (US);

Inventors:

Ambuj K. Singh, Santa Barbara, CA (US);

Christian A. Lang, Santa Barbara, CA (US);

Assignee:

ACELOT, INC., Palo Alto, CA (US);

Attorney:

Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.

Primary Examiner:

Douglas M Willis

Int. Cl.
CPC ...
C07C 211/23 (2006.01); C07C 233/43 (2006.01); C07C 271/18 (2006.01); A61K 31/135 (2006.01); A61K 31/137 (2006.01); C07C 223/02 (2006.01); C07C 211/28 (2006.01); C07C 211/29 (2006.01); A61K 31/131 (2006.01); C07C 211/27 (2006.01); C07C 217/60 (2006.01); C07D 207/06 (2006.01); C07D 295/135 (2006.01); C07D 295/15 (2006.01); C07D 319/18 (2006.01); C07D 413/06 (2006.01);
U.S. Cl.
CPC ...
C07C 233/43 (2013.01); A61K 31/131 (2013.01); A61K 31/135 (2013.01); A61K 31/137 (2013.01); C07C 211/27 (2013.01); C07C 211/28 (2013.01); C07C 211/29 (2013.01); C07C 217/60 (2013.01); C07C 223/02 (2013.01); C07C 271/18 (2013.01); C07D 207/06 (2013.01); C07D 295/135 (2013.01); C07D 295/15 (2013.01); C07D 319/18 (2013.01); C07D 413/06 (2013.01);
Abstract

The present disclosure provides small molecule drugs and pharmaceutical compositions for the treatment and prevention of diseases related to the formation of Aβ42 oligomers in a subject. It further provides a method of reducing formation of or disrupting Aβ42 oligomers in a subject, the method comprising the step of administering to the subject in need thereof a therapeutically effective amount of a pharmaceutical composition. One such compound is a compound of formula 120:

Find Patent Forward Citations

Quick Actions:

Singh, Ambuj. (2023). Substituted amines as disrupters of abeta42 oligomer formation (U.S. Patent No. 11827582). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11827582

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