The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 28, 2023

Filed:

Oct. 18, 2021
Applicants:

Tangyi Holdings (Shenzhen) Limited, Shenzhen, CN;

Healthina Stem Cell Industry Platform (Tianjin) Limited, Tianjin, CN;

Inventors:

Bin Zheng, Shenzhen, CN;

Yulin Cao, Shenzhen, CN;

Bowen Li, Shenzhen, CN;

Wei Sun, Shenzhen, CN;

Shixiang Cheng, Shenzhen, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61M 3/00 (2006.01); A61K 9/00 (2006.01); A61K 35/28 (2015.01); C12N 5/00 (2006.01); A61M 37/00 (2006.01); B29C 41/04 (2006.01); B29C 41/38 (2006.01); C12N 5/0775 (2010.01); B29L 31/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0021 (2013.01); A61K 35/28 (2013.01); A61M 37/0015 (2013.01); B29C 41/04 (2013.01); B29C 41/38 (2013.01); C12N 5/0663 (2013.01); A61M 2037/0023 (2013.01); A61M 2037/0053 (2013.01); B29K 2883/00 (2013.01); B29L 2031/7544 (2013.01);
Abstract

The present invention discloses a nano-armored single cell product, comprising a liposome and probiotics encapsulated by the liposome, wherein the probiotics are fermented to produce gamma-aminobutyric acid (GABA) that alleviates the activation of an inflammatory response in substantia nigra inducedin a MPTP induced PD model, thus mitigating an inflammatory injury to dopaminergic neurons in substantia nigra and having a neuroprotective effect; encapsulation of the probiotics by the liposome can protect the probiotics from strong acids and digestive enzymes in gastric acid.


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