The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 28, 2023
Filed:
Dec. 22, 2020
Applicant:
University of Massachusetts, Boston, MA (US);
Inventors:
Guangping Gao, Worcester, MA (US);
Phillip D. Zamore, Worcester, MA (US);
Assignee:
University of Massachusetts, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/86 (2006.01); A61K 48/00 (2006.01); C12N 15/11 (2006.01); C12N 15/85 (2006.01); A01K 67/027 (2006.01); A61K 38/00 (2006.01); C12N 7/00 (2006.01); C12N 15/113 (2010.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 48/0008 (2013.01); A01K 67/0275 (2013.01); A61K 9/0019 (2013.01); A61K 38/00 (2013.01); A61K 48/0058 (2013.01); C12N 7/00 (2013.01); C12N 15/111 (2013.01); C12N 15/113 (2013.01); C12N 15/8509 (2013.01); C12N 15/86 (2013.01); A01K 2207/05 (2013.01); A01K 2217/058 (2013.01); A01K 2227/105 (2013.01); A01K 2267/03 (2013.01); A01K 2267/0331 (2013.01); C12N 2015/8527 (2013.01); C12N 2310/13 (2013.01); C12N 2310/141 (2013.01); C12N 2320/32 (2013.01); C12N 2330/51 (2013.01); C12N 2710/10342 (2013.01); C12N 2750/14143 (2013.01); C12N 2750/14145 (2013.01); C12N 2820/002 (2013.01); C12N 2840/007 (2013.01); C12N 2840/102 (2013.01);
Abstract
The invention in some aspects relates to isolated nucleic acids, compositions, and kits useful for identifying adeno-associated viruses in cells. In some aspects, the invention provides kits and methods for producing somatic transgenic animal models using recombinant AAV (rAAV) to an animal having at least one transgene that expresses a small interfering nucleic acid or at least one binding site for a miRNA.