The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 28, 2023

Filed:

Sep. 13, 2017
Applicant:

Versitech Limited, Pokfulam, HK;

Inventors:

Philip Man Lung Yeung, Kowloon, HK;

Fuk Woo Jasper Chan, Kowloon, HK;

Manson Fok, Mid-Levels Central, HK;

Johnson Yiu-Nam Lau, Houston, TX (US);

Kwok-Yung Yuen, Pokfulam, HK;

Assignee:

VERSITECH LIMITED, Hong Kong, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/42 (2006.01); A61P 31/12 (2006.01); C07K 16/40 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/42 (2013.01); A61P 31/12 (2018.01); C07K 16/40 (2013.01); A61K 2039/57 (2013.01);
Abstract

Enteroviruses, such as EV-A71, have been found to utilize hWARS as a cell surface receptor, with expression ofhWARS rendering cells susceptible to enteroviral infection. Reduction in hWARS cell surface activity reduces susceptibility to enteroviral infection and provides a mode for treatment or prevention of enteroviral infection and its sequelae. Similarly, expression of hWARS in cultured cells and animal models provides models for understanding enteroviral disease mechanisms and the development of vaccines and/or pharmaceuticals for preventing or treating enteroviral disease.


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