The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 28, 2023

Filed:

Jun. 22, 2018
Applicant:

Prometic Biotherapeutics, Inc., Rockville, MD (US);

Inventors:

Lyne Gagnon, Laval, CA;

Brigitte Grouix, Laval, CA;

Pierre Laurin, Ville Mont-Royal, CA;

Assignee:

PROMETIC BIOTHERAPEUTICS, INC., Rockville, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/48 (2006.01); A61P 11/00 (2006.01); A61K 31/4418 (2006.01);
U.S. Cl.
CPC ...
A61K 38/484 (2013.01); A61K 31/4418 (2013.01); A61P 11/00 (2018.01);
Abstract

The present invention concerns the use of plasminogen, a variant thereof, or an analog thereof having a plasminogen activity, for the prevention or treatment of a condition or a disease that is characterized with an increased PAI-1 level. The conditions and diseases that are characterized with an increased PAI-1 level, are regrouped within two categories: the diseases associated with an impaired vascular or tissue remodeling capacity, and the metabolic and hormonal disorders associated with an increased PAI-1 level.


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