The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 28, 2023

Filed:

Nov. 12, 2021
Applicant:

Loxo Oncology, Inc., Indianapolis, IN (US);

Inventor:

Nicolas Guisot, Cheshire, GB;

Assignee:

Loxo Oncology Inc., Indianapolis, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/415 (2006.01); C07D 405/14 (2006.01); C07D 231/14 (2006.01); C07D 401/04 (2006.01); C07D 401/06 (2006.01); C07D 403/04 (2006.01); C07D 405/04 (2006.01); C07D 405/08 (2006.01); C07D 413/06 (2006.01); A61K 45/06 (2006.01); C07D 405/06 (2006.01); A61P 37/02 (2006.01); A61P 35/02 (2006.01); C07D 231/38 (2006.01); A61P 35/00 (2006.01); A61K 31/4155 (2006.01); C07D 417/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/415 (2013.01); A61K 31/4155 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); A61P 35/02 (2018.01); A61P 37/02 (2018.01); C07D 231/14 (2013.01); C07D 231/38 (2013.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01); C07D 403/04 (2013.01); C07D 405/04 (2013.01); C07D 405/06 (2013.01); C07D 405/08 (2013.01); C07D 405/14 (2013.01); C07D 413/06 (2013.01); C07D 417/04 (2013.01);
Abstract

This invention relates to novel compounds. The compounds of the invention are tyrosine kinase inhibitors. Specifically, the compounds of the invention are useful as inhibitors of Bruton's tyrosine kinase (BTK). The invention also contemplates the use of the compounds for treating conditions treatable by the inhibition of Bruton's tyrosine kinase, for example cancer, lymphoma, leukemia and immunological diseases.


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