The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 28, 2023
Filed:
Oct. 01, 2020
Applicant:
Cognitive Research Enterprises, Inc., Morgantown, WV (US);
Inventor:
Daniel L. Alkon, Chevy Chase, MD (US);
Assignee:
Synaptogenix, Inc., New York, NY (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/366 (2006.01); A61K 31/365 (2006.01); A61P 25/28 (2006.01); A61K 9/00 (2006.01); A61P 25/26 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
A61K 31/366 (2013.01); A61K 9/0019 (2013.01); A61K 31/365 (2013.01); A61P 25/26 (2018.01); A61P 25/28 (2018.01); C07K 14/4713 (2013.01);
Abstract
Dosing regimens and methods are disclosed for upregulating protein kinase C (PKC) while reducing subsequent downregulation, comprising administering a PKC activator once a week for three consecutive weeks followed by cessation of administration or dosing for three consecutive weeks. Also described are methods for improving or enhancing cognitive ability, preventing or treating cognitive impairment, preventing or treating a neurodegenerative disease or condition, and/or preventing or treating a disease or condition associated with neuronal or synaptic loss according to the disclosed regimens.