The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 28, 2023

Filed:

Mar. 05, 2021
Applicant:

Depuy Synthes Products, Inc., Raynham, MA (US);

Inventors:

Malavosklish Bikram-Liles, Paoli, PA (US);

Charles Florek, Downingtown, PA (US);

David A. Armbruster, West Chester, PA (US);

Shireen Shaikh, Bear, DE (US);

Kyra Woloszczuk, Churchville, PA (US);

Assignee:

DePuy Synthes Products, Inc., Raynham, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/201 (2006.01); A61P 31/04 (2006.01); A61K 31/546 (2006.01); A61K 31/7036 (2006.01); A61K 38/14 (2006.01); A61L 27/54 (2006.01);
U.S. Cl.
CPC ...
A61K 31/201 (2013.01); A61K 31/546 (2013.01); A61K 31/7036 (2013.01); A61K 38/14 (2013.01); A61L 27/54 (2013.01); A61P 31/04 (2018.01);
Abstract

Provided herein are compositions for treating biofilm-derived infections include a cis-monounsaturated fatty acid solubilized in a solvent with a concentration in the range of about 100 ppm (parts per million) to about 1000 ppm, where the composition is configured to produce a bactericidal effect measured as a log reduction of colony forming units (CFU) of a bacteria of at least 1.0 when the composition is applied to a biofilm formed from the bacteria. Also provided are methods for treating the site of a biofilm-derived infection comprising applying a composition as disclosed herein to the site.


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