The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 28, 2023
Filed:
Mar. 29, 2018
Mark Trifiro, Montreal, CA;
Miltiadis Paliouras, Laval, CA;
Lenore K. Beitel, Montreal, CA;
Carlos Alvarado, Dollard des Ormeaux, CA;
Mark Trifiro, Montreal, CA;
Miltiadis Paliouras, Laval, CA;
Lenore K. Beitel, Montreal, CA;
Carlos Alvarado, Dollard des Ormeaux, CA;
Abstract
A knock-in non-human mammal comprising a recombinant androgen receptor (AR) cassette containing an exogenous human polyglutamine (polyQ) tract encoding sequence in exon 1, wherein the human polyQ tract encoding sequence is stably integrated into the genome of the animal. Also provided are recombinant cells, fertilized eggs and tissues. The resulting animal displays a wide range of phenotypes, best characterized as Metabolic Syndrome and can be used in screening and other assays.