The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 28, 2023
Filed:
Apr. 11, 2020
Seoul National University Hospital, Seoul, KR;
Seoul National University R&db Foundation, Seoul, KR;
The Catholic University of Korea Industry-academic Cooperation Foundation, Seoul, KR;
Hee Seung Kim, Seoul, KR;
Jeong Mook Lim, Seoul, KR;
Ji Yeon Ahn, Seoul, KR;
Na Ra Lee, Seoul, KR;
Eun Ji Lee, Seoul, KR;
Soo Jin Park, Seoul, KR;
Sung Jong Lee, Seoul, KR;
Abstract
The present invention relates to a method for preparing a large animal model, with peritoneal carcinomatosis, which is an abdominal cavity metastasis of tumor commonly found in advanced or recurrent solid cancer, is induced using a large animal, and the method for preparing a large animal model with peritoneal carcinomatosis comprises injecting a cancer cell line into the abdominal cavity of a piglet in which the immune function is not completed. The method for preparing a large animal model with peritoneal carcinomatosis, when a human-derived immortalized cell line is inoculated into a pig, can overcome xenograft rejection and induce peritoneal carcinomatosis, can use animals with sufficient supply and demand, and can expect the spread of peritoneal carcinomatosis through breeding.